Status:

RECRUITING

Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia

Lead Sponsor:

Johannes Gutenberg University Mainz

Conditions:

Agoraphobia; Panic

Social Anxiety Disorder

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Anxiety disorders, including agoraphobia, are prevalent in the German population, leading affected individuals to avoid specific places like crowds or public transport. Although cognitive-behavioral t...

Detailed Description

Anxiety disorders are among the most common mental illnesses in the German population. Agoraphobia is an anxiety disorder characterized by the avoidance of specific places. Individuals affected by ago...

Eligibility Criteria

Inclusion

  • Experimental group: Diagnosis of agoraphobia with or without panic disorder
  • Clinical control group: diagnosis of social phobia
  • Control group: healthy individuals without acute or chronic mental illness
  • A depressive disorder may be present as a comorbid diagnosis in the experimental group and the clinical control group

Exclusion

  • Other mental illnesses: Substance dependence, schizophrenia, bipolar disorder, dementia, eating disorders, PTSD, major depressive episode, personality disorder
  • Somatic diseases: Cancer, cardiovascular diseases, epilepsy, autoimmune diseases, metabolic or endocrine diseases
  • Taking psychotropic medication (except antidepressants) or medication that affects the cardiovascular system (e.g. beta-blockers), medication containing cortisone, use of creams with corticosteroids
  • Pregnancy, breastfeeding
  • Ongoing psychotherapy

Key Trial Info

Start Date :

May 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2027

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT06514495

Start Date

May 1 2025

End Date

August 1 2027

Last Update

September 3 2025

Active Locations (1)

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1

University Medical Center

Mainz, Germany, 55122