Status:

RECRUITING

Association of Middle Molecules Clearance With HDF Volume

Lead Sponsor:

East and North Hertfordshire NHS Trust

Conditions:

End Stage Renal Disease

Eligibility:

All Genders

18+ years

Brief Summary

HDF is a dialysis technique which involves diffusion and convection. HDF with high convection volume has consistently shown to improve survival in dialysis patients in number of robust RCTs. The preci...

Detailed Description

People with severe kidney failure need treatment by dialysis or transplantation to stay alive. In the UK there are 25,000 people receiving treatment with haemodialysis (HD). Conventional haemodialysis...

Eligibility Criteria

Inclusion

  • Age 18 years or above.
  • Ability to give informed consent.
  • End stage renal failure treated by dialysis for at least 3 months.
  • Established on hemodiafiltration for \>4 weeks.
  • Prognosis more than 6 months as assessed by PI

Exclusion

  • Age less than 18 years.
  • Inability to give informed consent.
  • Prognosis less than 6 months as assessed by PI

Key Trial Info

Start Date :

January 19 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT06515899

Start Date

January 19 2024

End Date

July 1 2025

Last Update

July 23 2024

Active Locations (1)

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1

East and North Hertfordshire NHS Trust

Stevenage, Hertfordshire, United Kingdom, SG1 4AB