Status:
RECRUITING
Impact 360 for Healthy Agers
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
The Jack and Darlene Poole Foundation
Conditions:
Healthy Aging
Eligibility:
All Genders
50-75 years
Phase:
NA
Brief Summary
The Impact 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes. 60 subjects...
Detailed Description
Current research suggests that exercise, meditation, and nutrition have neuroprotective effects although there is still a lack of pharmacological therapies to prevent or slow down disease progression....
Eligibility Criteria
Inclusion
- Participants who are able to complete questionnaires and follow directions for interventions
- Have access to a smartphone that can support the Fitbit app
Exclusion
- Any neurological disease/disorder diagnosis (Ex: Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, Brain lesion, Stroke, etc)
- Any chronic medical condition which would affect ability to participate in exercise
- Any contraindication for exercise based on the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and medical clearance form
- Participants who were told by a medical doctor that they need to be medically supervised for exercise
- Montreal Cognitive Assessment (MoCA) scores \<21/30
- Significant cognitive impairment, depression, or eating disorder
- Any contraindication to MRI scanning; such as implanted metal clips or wires (see list below)
- Participants currently doing 180 minutes or more of moderate-vigorous intensity exercise per week AND either of the following:
- Completion of an Mindfulness-Based Stress Reduction course OR; Score \>8/15 in the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) Diet Questionnaire
- Significant or unstable cardiovascular or respiratory disease
- Severe/multiple head trauma(s)
- Subjects who are pregnant or breastfeeding
- Subjects with a history or major episodes of drug or alcohol abuse
- Chronic/acute bacterial/viral infection
- GI cancer
- Inflammatory bowel disease
- Exclusion for MRI scanning:
- Individuals weighing \> 400 lbs (limit of MRI machine)
- Artificial heart valve
- Brain aneurysm clip
- Electrical stimulator for nerves or bones
- Ear or eye implant
- Implanted drug infusion pump
- Coil, catheter, or filter in any blood vessel
- Orthopedic hardware (artificial joint, plate, screws)
- Other metallic prostheses
- Shrapnel, bullets, or other metal fragments
- Surgery or tattoos (including tattooed eyeliner) in the last six weeks
- Brain surgery
- Have a cardiac pacemaker, wires or defibrillator
- Have had an injury where a piece of metal lodged in the eye or orbit
- Have a ferromagnetic aneurysm clip
Key Trial Info
Start Date :
January 24 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 5 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06516146
Start Date
January 24 2024
End Date
January 5 2025
Last Update
July 23 2024
Active Locations (1)
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1
University of British Colombia
Vancouver, British Columbia, Canada, V6T 1Z3