Status:

RECRUITING

Spatially and Temporally Resolving Predictive Biomarkers of Postoperative Recurrence and Complications in Chronic Intestinal Inflammation

Lead Sponsor:

IRCCS Ospedale San Raffaele

Collaborating Sponsors:

IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo

Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona

Conditions:

Ulcerative Colitis

Crohn Disease

Eligibility:

All Genders

18-69 years

Brief Summary

A portion of patients with Inflammatory bowel disease often require surgical intervention since they do not respond to the current therapies. Besides this risk, patients may develop post-operative dis...

Detailed Description

A portion of patients with Inflammatory bowel disease often require surgical intervention since they do not respond to the current therapies. Besides this risk, patients may develop post-operative dis...

Eligibility Criteria

Inclusion

  • adult (age \>18 years) patients with histologically confirmed CD or UC undergoing intestinal resection due to stricturing disease, regardless of their current or past medical treatment;
  • given that it is an observational study, also pregnant and breastfeeding patients could be included;
  • able and willing to sign the informed consent.

Exclusion

  • patients \<18 years or \> 70 years;
  • patients with unconfirmed both UC and CD diagnoses;
  • patients with superimposed dysplasia or cancer diagnosis and resections for which post- operative endoscopic assessment of recurrence is not feasible;
  • patients unable or unwilling to sign the informed consent.

Key Trial Info

Start Date :

February 27 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT06516341

Start Date

February 27 2025

End Date

September 1 2026

Last Update

March 14 2025

Active Locations (1)

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IRCCS Ospedale San Raffaele

Milan, Italy, Italy, 20132

Spatially and Temporally Resolving Predictive Biomarkers of Postoperative Recurrence and Complications in Chronic Intestinal Inflammation | DecenTrialz