Status:
RECRUITING
Spinal Networks of Balance Learning and Retention in Older Adults
Lead Sponsor:
University of Florida
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Aging
Eligibility:
All Genders
65-95 years
Phase:
NA
Brief Summary
Age-related balance and walking issues increase fall risks, leading to injuries, higher healthcare costs, reduced quality of life, and increased morbidity/mortality rates. Preserving functional abilit...
Detailed Description
A high proportion of older adults are currently or soon will be at risk for the well-known decline in walking and balance abilities that occur with aging. Preserving those abilities has become a major...
Eligibility Criteria
Inclusion
- age range: 65 to 95 years
- no severe high blood pressure: Resting systolic \< 180 mmHg and diastolic \< 100 mmHg
- no severe vision impairment: Visual acuity ≥ 20/70 as determined by Snellen eye chart
- walking problem: Preferred walking speed slower than 1.0 m/s over 10 meters
- balance problem: Berg Balance Scale score \< 45
- no cognitive impairment: Montreal Cognitive Assessment (MoCA) score ≥ 26 out of 30
Exclusion
- diagnosed neurological disorder or injury of the central nervous system, or observation of symptoms consistent with such a condition (Alzheimer's, Parkinson's, stroke, etc.)
- severe arthritis, such as awaiting joint replacement
- current cardiovascular, lung or renal disease; untreated diabetes; terminal illness
- myocardial infarction or major heart surgery in the previous year
- cancer treatment in the past year, except for nonmelanoma skin cancers and cancers having an excellent prognosis (e.g., early stage breast or prostate cancer)
- current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder
- currently taking medications that affect the central nervous system, such as benzodiazepines, anti-cholinergic medication, and GABAergic medication, among others
- uncontrolled hypertension at rest (systolic \> 180 mmHg and/or diastolic \> 100 mmHg)
- bone fracture or joint replacement in the previous six months
- current enrollment in any other clinical trial
- planning to relocate out of the area during the study period
- non-English\* speaking, due to the likelihood of difficulties following instructions and communicating remotely
- clinical judgment of the investigative team
Key Trial Info
Start Date :
January 22 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06517043
Start Date
January 22 2025
End Date
August 31 2026
Last Update
May 13 2025
Active Locations (1)
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1
Malcom Randall VA Medical Center Brain Rehabilitation Research Center
Gainesville, Florida, United States, 32608