Status:
RECRUITING
Emotion and Memory in Chronic Neuropathic Pain
Lead Sponsor:
University Health Network, Toronto
Conditions:
Trigeminal Neuralgia
Facial Pain
Eligibility:
All Genders
35-60 years
Brief Summary
Chronic pain affects one in four Canadians, leading to severe personal and societal costs. Over 70% of chronic pain patients report memory difficulties and fear having unexpected pain. Abnormalities i...
Detailed Description
Chronic pain affects 1 in 4 Canadians leading to severe personal and societal consequences. Over 70% of patients with chronic pain report cognitive deficits including memory difficulties and fear of h...
Eligibility Criteria
Inclusion
- Inclusion Criteria (for HC and TN):
- Age between 35 and 60 years old
- Absence of other active major neurological or psychiatric disorders
- Absence of MRI contraindications
- Able to communicate sufficiently to complete tasks and questionnaires
- Montreal Cognitive Assessment (MoCA) score greater than 23/30 (MoCA ≤23/30 could indicate severe cognitive impairment)
- Inclusion Criteria for TN:
- Experiencing TN pain over a period of 6 months
- Stable medication use
- Meet established diagnostic criteria for TN (ICHD-3)
- Exclusion Criteria (both HC and TN):
- Presence of other chronic pain/headache conditions
- Untreated hypertension or diabetes mellitus
- History of chronic drug or substance use disorder, chronic use of opioids or steroids, head trauma affecting cognitive performance,
- History/presence of active psychiatric illness and/or current use of psychoactive medication
- History of multiple sclerosis, skull base injury or tumours
Exclusion
Key Trial Info
Start Date :
February 12 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 12 2029
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06518421
Start Date
February 12 2024
End Date
February 12 2029
Last Update
July 24 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Toronto Western Hospital
Toronto, Ontario, Canada, M5T2S8