Status:
RECRUITING
Early Neurovascular Adaptations in Aging Women
Lead Sponsor:
University of Missouri-Columbia
Collaborating Sponsors:
American Heart Association (AHA)
Conditions:
Women
Sympathetic Nervous System
Eligibility:
FEMALE
18-70 years
Phase:
EARLY_PHASE1
Brief Summary
Our goal is to enhance our understanding of early vascular adaptations in aging women with an emphasis on the sympathetic nervous system.
Eligibility Criteria
Inclusion
- Assigned female at birth (AFAB)
- 18-70 years of age
Exclusion
- Assigned male at birth (AMAB)
- Pregnancy, breastfeeding
- Body mass index ≥30 kg/m2
- Taking medications known to affect metabolic, autonomic, and/or respiratory function
- Oral hormonal contraception in last 6 month
- History of hormone replacement therapy
- History of hyster- or oophor-ectomy
- Current smoking/Nicotine use
- Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
- Chronic disease
- Blood pressure ≥140/90 mmHg
- Communication barriers
Key Trial Info
Start Date :
September 20 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2028
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT06520982
Start Date
September 20 2024
End Date
June 30 2028
Last Update
November 26 2025
Active Locations (1)
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1
University of Missouri-Columbia
Columbia, Missouri, United States, 65211