Status:
NOT_YET_RECRUITING
Role of Follicular T Cells in Hashimoto's Thyroiditis
Lead Sponsor:
Omnia Ahmed Nafea Mohamed
Conditions:
Hashimoto's Thyroiditis
Eligibility:
All Genders
18-75 years
Brief Summary
Measure the frequency of Follicular helper Tcells and Follicular regulatory T cells in peripheral blood samples in Hashimoto's pts in comparison with control.
Detailed Description
Hashimoto thyroiditis, also known as chronic autoimmune thyroiditis and chronic lymphocytic thyroiditis, is an autoimmune disease in which thyroid cells are destroyed via cell and antibody-mediated im...
Eligibility Criteria
Inclusion
- \- The study will include 45 Hashimoto's patients attending the out clinics of Endocrinology Department of Assiut university hospital. In addition, 45 healthy blood donors will be included as controls. The diagnosis of hashimoto's thyroiditis will be determined according to the criteria of American Thyroid Association;
- Having symptoms of hypothyroidism, and a blood test shows an underactive thyroid gland \[an elevated thyroid stimulating hormone (TSH) level with or without a low thyroid hormone (free T4 or total T4) level\].
- have elevated thyroid antibody levels.
- ultrasound examination demonstrating characteristic heterogeneous echotexture.
- results of thyroid fine needle aspiration (FNA) examinations meeting HT cytology diagnostic criteria.
Exclusion
- -We should exclude other causes of thyroiditis, such as De Quervain's thyroiditis, Riedel's thyroiditis, and suppurative thyroiditis and also exclude other autoimmune diseases for example; type1 diabetes\&Rheumatoid arthritis,and other diseases which cause hypothyroidism as carcinoma and surgery.
Key Trial Info
Start Date :
May 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06521359
Start Date
May 1 2025
End Date
June 1 2026
Last Update
July 25 2024
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.