Status:

ENROLLING_BY_INVITATION

Hippocampal Network Function in Epilepsy

Lead Sponsor:

University of Chicago

Conditions:

Mesial Temporal Lobe Epilepsy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this pilot study is to understand hippocampal network function in mesial temporal lobe epilepsy (MTLE) and to test whether transcranial magnetic stimulation (TMS) targeting the network of t...

Detailed Description

The purpose of this pilot study is to investigate hippocampal network dysfunction associated with mesial temporal lobe epilepsy (MTLE) and to examine whether network-targeted transcranial magnetic sti...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Diagnosis of (pharmacoresistant) MTLE
  • Age 18+ years old
  • Native English speakers
  • Normal or corrected-to-normal near and far vision
  • Stable antiepileptic drugs (AED) regimen (unchanged for at least 1 month)
  • Exclusion criteria:
  • Diagnosis of neurological illness other than MTLE
  • Taking drugs that impair cognition other than anticonvulsive medication for the treatment of MTLE (e.g., antipsychotics or psychostimulants).
  • Children under the age of 18 years

Exclusion

    Key Trial Info

    Start Date :

    July 1 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2028

    Estimated Enrollment :

    34 Patients enrolled

    Trial Details

    Trial ID

    NCT06521437

    Start Date

    July 1 2024

    End Date

    December 1 2028

    Last Update

    September 12 2025

    Active Locations (1)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (1 locations)

    1

    University of Chicago

    Chicago, Illinois, United States, 60637