Status:

RECRUITING

Nerve Grafting Technique to Preserve Erectile Function in Patients Undergoing Robotic Assisted Radical Prostatectomy

Lead Sponsor:

Sir Mortimer B. Davis - Jewish General Hospital

Conditions:

Prostate Cancer

Erectile Dysfunction

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

The investigator proposing a single arm prospective pilot trial evaluating the safety and the 1-year erectile recovery outcomes of patients undergoing Nerve Restoring (NR) Robotically assisted laparos...

Detailed Description

Patients will have baseline evaluation with International Index of Erectile Function-5 (IIEF-5) questionnaire and the Short Form McGill Pain Questionnaire (SF-MPQ)1, which will be re-evaluation at tim...

Eligibility Criteria

Inclusion

  • Patients undergoing standard of care robotic radical prostatectomy for high-risk localized prostate cancer as defined by any of:
  • Gleason grade ≥8
  • PSA ≥20
  • \>pT2 on preoperative MRI imaging
  • Patients must have preoperative erectile function with a baseline IIEF score of ≥17

Exclusion

  • Patients with previous pelvic surgery
  • Patients with previous pelvic radiotherapy
  • Patient with previous focal therapy for prostate cancer
  • Patients aged \< 18 years at diagnosis
  • Legally incapable patients
  • Patients who are unable to complete questionnaires and have no companion to help complete them
  • Patients undergoing a concomitant cancer surgery
  • Patients with pre-existing neurologic disease

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06521710

Start Date

September 1 2024

End Date

December 1 2027

Last Update

September 19 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Jewish General Hospital, CIUSSS Centre-Ouest de l&#39;île de Montréal

Montreal, Quebec, Canada, H3T 1E2

2

Jewish General Hospital

Montreal, Quebec, Canada, H3T 1E2