Status:
ACTIVE_NOT_RECRUITING
Distribution of Bacteria in OME After Radiotherapy For NPC.
Lead Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Conditions:
Otitis Media Effusion
Nasopharyngeal Carcinoma
Eligibility:
All Genders
15-70 years
Brief Summary
To observe the prognostic difference of tympanocentesis in different kinds of otitis media effusion.
Detailed Description
This study is a prospective, observational clinical study to observe the difference in prognosis of tympanocentesis in different kinds of otitis media effusion (OME), especially OME after radiotherapy...
Eligibility Criteria
Inclusion
- patients clinical diagnosis of OME or OME after radiotherapy for NPC (Diagnostic criteria: fluid visible in the middle ear and a type B tympanogram).
- patients volunteered to participate in the study and signed the informed consent
Exclusion
- NPC recurrence or other malignant tumor after radiotherapy.
- clear diagnosis of Eustachian ostium atresia or nasal obstruction diseases, such as severe deviated nasal septum, choanal atresia, osteoradionecrosis of skull base after radiotherapy, etc.
- pregnant and lactating women.
- patients with severe underlying diseases or with severe liver and kidney dysfunction.
- patients who could not cooperate (including poor hearing and radiation encephalopathy)
- patients with other middle ear diseases, such as middle ear cholesteatoma, osteoradionecrosis of temporal bone after radiotherapy, etc.
- severe deglutition disorders
- cleft palate
Key Trial Info
Start Date :
May 12 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 12 2025
Estimated Enrollment :
234 Patients enrolled
Trial Details
Trial ID
NCT06523933
Start Date
May 12 2024
End Date
May 12 2025
Last Update
July 26 2024
Active Locations (1)
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1
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510120