Status:

COMPLETED

MRD Detection by NGS in Pediatric T-ALL

Lead Sponsor:

The Children's Hospital of Zhejiang University School of Medicine

Conditions:

Acute Lymphoblastic Leukemia, Pediatric

Eligibility:

All Genders

1-18 years

Brief Summary

This retrospective analysis aims to investigate pediatric patients with T cell acute lymphoblastic leukemia who were detected for minimal residual disease (MRD) using next-generation sequencing (NGS)....

Detailed Description

This was a prospective, single-center, observational study conducted in children with ALL between February 2018 and December 2022. Children with newly diagnosed T-ALL who undergone NGS of T-cell recep...

Eligibility Criteria

Inclusion

  • Children with newly diagnosed T-ALL who undergone NGS of T-cell receptors

Exclusion

  • T-ALL patients who have not undergone high-throughput sequencing.
  • T-ALL Patients without traceable significant clones.

Key Trial Info

Start Date :

February 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

69 Patients enrolled

Trial Details

Trial ID

NCT06525116

Start Date

February 1 2018

End Date

December 31 2022

Last Update

July 29 2024

Active Locations (1)

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The Children's Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310003