Status:
RECRUITING
New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
Lead Sponsor:
National and Kapodistrian University of Athens
Collaborating Sponsors:
National Hellenic Research Foundation
Conditions:
Osteoporosis, Postmenopausal
Osteoporosis Fracture
Eligibility:
FEMALE
Brief Summary
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics. By analyzing bone and plasm...
Detailed Description
Study Objectives: 1. To investigate the proteomic profile of bone and plasma in clinical osteoporosis compared to patients with osteoarthritis. 2. To study the metabolomic profile of serum in clinica...
Eligibility Criteria
Inclusion
- Postmenopausal Female Patients with osteoporotic subcapital femoral neck fracture (Arm 1)
- Postmenopausal Female Patients with hip osteoarthritis that will undergo Total Hip Replacement (Arm 2)
Exclusion
- Patients that have undergone before osteoporotic fractures
- Patients with severe cardiovascular, pulmonary, autoimmune, or urinary system conditions
Key Trial Info
Start Date :
July 3 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06525688
Start Date
July 3 2024
End Date
December 30 2025
Last Update
July 29 2024
Active Locations (1)
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1
Laboratory for Research of the Musculoskeletal System
Kifissia, Attica, Greece, 14561