Status:

NOT_YET_RECRUITING

Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder

Lead Sponsor:

University of Colorado, Denver

Collaborating Sponsors:

National Institutes of Health (NIH)

National Institute on Drug Abuse (NIDA)

Conditions:

Medication Abuse

Harm Reduction

Eligibility:

All Genders

12-89 years

Brief Summary

The objective of this study is to evaluate the impact of clinical decision support (CDS) in the form of an alert to identify patients who may be at risk of opioid use disorder (OUD) and a clinical car...

Eligibility Criteria

Inclusion

  • Primary care encounter AND
  • Current opioid prescription (not buprenorphine) and Active opioid medications over the last 90 days OR
  • Documented as on local Pain Registry "Does the patient fit the criteria to be included on the Pain Registry?" OR
  • Has active problem list diagnosis of long-term (current) use of opiate analgesic OR
  • Is taking \>=90 morphine milligram equivalents (MME) per day OR
  • Prior positive toxicology screen for illicit drugs OR
  • Diagnosis of opioid use disorder

Exclusion

  • Active cancer diagnosis in the last 1 year
  • Hospice care/palliative care order
  • Sickle cell disease diagnosis

Key Trial Info

Start Date :

February 1 2026

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2027

Estimated Enrollment :

200000 Patients enrolled

Trial Details

Trial ID

NCT06526286

Start Date

February 1 2026

End Date

May 1 2027

Last Update

December 10 2025

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