Status:
NOT_YET_RECRUITING
Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)
Lead Sponsor:
Womack Army Medical Center
Collaborating Sponsors:
University of Kentucky
Conditions:
Chronic Ankle Instability
Eligibility:
All Genders
18-44 years
Phase:
NA
Brief Summary
The purpose of this study is to examine the effectiveness of a novel ankle rehabilitation protocol on improving clinical and health outcomes in physically active individuals with chronic ankle instabi...
Detailed Description
Military personnel and physically active civilians are particularly vulnerable to ankle sprains and subsequent chronic ankle instability (CAI). CAI is a complex neuromusculoskeletal condition characte...
Eligibility Criteria
Inclusion
- Physically active and engage in regular exercise/training
- 18-44 years old (accounts for 86% of the individuals deployed in recent military conflicts)
- Answer "yes" to Question 1 (i.e., have you ever sprained an ankle?) on the Ankle Instability Instrument
- Answer "yes" to any four of the remaining Ankle Instability Instrument questions
- Score \<24 on the Cumberland Ankle Instability Tool
- Report at least two episodes of the ankle "giving way" in the last six months
- Access to a functional email address and internet for completion of health and Service member outcomes
- Ability to provide informed consent
Exclusion
- Unable to read or comprehend the English language.
- An ankle sprain within the last six (≤6) weeks that resulted in altered or missed physical activity for one or more (≥1) consecutive days.
- History of ankle surgery.
- History of lower extremity fracture in the last year or history of fracture that required fixation.
- Any peripheral neuropathies or other health conditions/current musculoskeletal injuries that may influence balance.
- Pregnant females (will be eligible for participation in the study after delivery of the baby and medical clearance by a qualified and licensed healthcare provider).
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 14 2027
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT06527287
Start Date
September 1 2025
End Date
June 14 2027
Last Update
April 4 2025
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