Status:

RECRUITING

the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

Central Serous Chorioretinopathy

Eligibility:

All Genders

Phase:

NA

Brief Summary

To investigate the potential association between gut microbiota and central serous chorioretinopathy (CSC), we have observed in our clinical practice that CSC patients often experience chronic gastroi...

Eligibility Criteria

Inclusion

  • Age 18 to 60 years
  • Diagnosis of acute central serous chorioretinopathy (CSC) (affected eye: ① FFA and ICGA showing typical CSC manifestations, ② presence of subretinal fluid (SRF) at the macular fovea, ③ disease duration ≤ 6 months)
  • Best Corrected Visual Acuity (BCVA): 53 to 86 letters
  • Other: No significant systemic diseases, signed informed consent, and able to commit to follow-up

Exclusion

  • Presence of significant systemic diseases
  • BCVA of 20/200 or worse
  • Presence of choroidal or retinal atrophy in the macular fovea of the affected eye
  • Presence of choroidal neovascularization (CNV), age-related macular degeneration (AMD), polypoidal choroidal vasculopathy (PCV), diabetic retinopathy (DR), choroidal hemangioma, pigment epithelial detachment (PED), etc., in the affected eye
  • High myopia in the affected eye

Key Trial Info

Start Date :

May 27 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2026

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT06527326

Start Date

May 27 2024

End Date

July 1 2026

Last Update

July 30 2024

Active Locations (1)

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2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China

Hanzhou, Zhejiang, China, 310000

the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy | DecenTrialz