Status:
RECRUITING
Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
Lead Sponsor:
Purdue University
Conditions:
Healthy
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin. Along with in...
Detailed Description
The term prebiotic was established in 1995 and has since undergone several updates in definition. As of 2017, the International Scientific Association for Probiotics and Prebiotics (ISAPP) defines pre...
Eligibility Criteria
Inclusion
- adults aged 18-45
- BMI \>18.5 - \< 30 kg/m2
- Regular bowel movements (\> 4 days per week)
Exclusion
- Self-reported sensitivity to FODMAPs and following a low FODMAP diet ((FODMAPS stands for fermentable oligosaccharides, disaccharides, monosaccharides and polyols).
- Self-reported food allergies and sensitivities including gluten, dairy, nuts, soya and lactose etc.
- Self-reported antibiotic treatment in the past 6 months.
- Self-reported history of gastrointestinal disease and/or heart disease, cardiovascular, liver, and respiratory disorders, cancer and/or clinically relevant (pre) diabetes.
- Self-reported to having undergone major surgery of the gastrointestinal tract, with the exception of cholecystectomy and appendectomy.
- Self-reported smoking and/or self-reported drug or alcohol abuse.
- Self-reported history of psychiatric and/or mood disorders including eating disorders.
- Self-reported to be following a restrictive diet (i.e. ketogenic, intermittent fasting).
- Pregnant and lactating women.
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 30 2026
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT06528041
Start Date
August 1 2024
End Date
July 30 2026
Last Update
December 11 2025
Active Locations (1)
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1
Purdue University
West Lafayette, Indiana, United States, 47907