Status:
COMPLETED
Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery
Lead Sponsor:
Zhejiang Cancer Hospital
Conditions:
Anxiety State
Esketamine
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
To evaluate whether esketamine can relieve anxiety in patients undergoing abdominal tumor surgery.
Detailed Description
Hamilton anxiety Scale was used to screen patients with anxiety. Only patients with score ≥ 8 were enrolled. These patients were randomly assigned to the experimental group and control group. All pat...
Eligibility Criteria
Inclusion
- Patients undergoing abdominal tumor surgery;
- older than 18 years old and younger than 70 years old;
- ASA grade I-III；
- Hamilton anxiety scale ≥ 8.
Exclusion
- Having serious mental illness before surgery or on antipsychotic medication in the two weeks before screening;
- Severe organ function lesions such as heart failure (left ventricular ejection fraction \<30%), myocardial infarction, kidney failure (requiring kidney replacement therapy), liver function impairment (Child-Pugh grade C), etc.
- Patients arranged to receive general anesthesia combined with epidural anesthesia patients;
- Patients who cannot communicate, read or write due to visual, auditory, language or other reasons;
- Patients allergic to ketamine;
- Patients refused to use postoperative self-controlled intravenous analgesia pump;
- Patients refused to participate in the study.
Key Trial Info
Start Date :
August 5 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2025
Estimated Enrollment :
185 Patients enrolled
Trial Details
Trial ID
NCT06530706
Start Date
August 5 2024
End Date
June 30 2025
Last Update
September 16 2025
Active Locations (1)
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1
Zhejiang cancer hospital
Hangzhou, Zhejiang, China