Status:

RECRUITING

Precision Radiotherapy for Tumours Using Magnetic Resonance-guided Linear Accelerator (MR-Linac)

Lead Sponsor:

The Second Affiliated Hospital of Hainan Medical University

Conditions:

Overall Response Rate

Oncology

Eligibility:

All Genders

18-75 years

Brief Summary

Aim to observe the application of MR-Linac for precision radiotherapy of tumours, analyse its therapeutic effect, toxic and side effects,Characteristics of dosimetric parameters etc.

Detailed Description

Primary endpoint: · Overall response rate (ORR) : It refers to the proportion of patients whose tumor volume reduction reaches the pre-specified value and can maintain the minimum time requirement, w...

Eligibility Criteria

Inclusion

  • Patients are undergoing or have undergone imaging or treatment at the MR linac;
  • Age 18-75 years, male or female;
  • ECOG score 0-2, life expectancy \> 6 months;
  • Patients provide written informed consent.

Exclusion

  • Contraindications to MRI, such as claustrophobia and metallic or electronic implants incompatible with MRI;
  • The presence of severe comorbidities that, in the opinion of the investigator, · preclude the toleration or completion of radiotherapy;
  • Acute inflammatory disease requiring systemic therapy;
  • The presence of active infectious disease;
  • Pregnant women, nursing mothers, and patients planning to have children during the study period.

Key Trial Info

Start Date :

August 19 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

3000 Patients enrolled

Trial Details

Trial ID

NCT06531681

Start Date

August 19 2023

End Date

December 31 2028

Last Update

February 13 2025

Active Locations (1)

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1

The Second Affiliated Hospital of Hainan Medical University

Haikou, China, 570311