Status:

RECRUITING

Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance

Lead Sponsor:

Auburn University

Conditions:

Mood Disturbance

Eligibility:

All Genders

18-50 years

Phase:

EARLY_PHASE1

Brief Summary

The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main ...

Detailed Description

Clinical assessments will include phlebotomy (completed at weeks 0 and 8) and questionnaires which will be completed at weeks 0, 4, and 8 to assess changes in mood disorder symptomology and serum BDNF...

Eligibility Criteria

Inclusion

  • Adults age 18-50
  • Depression subscale score of \>9/21 on the DASS-21
  • No change in medications or supplements over the past 3 months
  • Can read and speak English

Exclusion

  • Currently consume curcumin or green tea daily
  • Currently, pregnant, nursing, or trying to become pregnant
  • Currently diagnosed with a perimenopausal disorder

Key Trial Info

Start Date :

September 30 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2025

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT06531863

Start Date

September 30 2024

End Date

August 1 2025

Last Update

February 14 2025

Active Locations (1)

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1

Auburn University School of Kinesiology

Auburn, Alabama, United States, 36849