Status:

COMPLETED

The PRICE Trial: Pain Reduction for Intrauterine Contraception Experiment

Lead Sponsor:

Mount Sinai Hospital, Canada

Conditions:

Contraception

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

Intrauterine devices (IUDs) are a highly effective form of reversible contraception with a less than 1% failure rate. They can be easily placed in the office and require little maintenance care. Howev...

Eligibility Criteria

Inclusion

  • Any participant presenting for an IUD placement, either for contraception or treatment of abnormal uterine bleeding or to regulate menstrual periods
  • All IUDs (copper, hormonal) eligible
  • All parities of patients are eligible

Exclusion

  • Use of pain medication that is not an NSAID or acetaminophen (e.g. opioids, benzodiazepines) within past 24 hours
  • Confirmed pregnancy
  • Any diagnosed chronic pain conditions (fibromyalgia, vaginismus, interstitial cystitis)
  • Misoprostol administration within 24 hours of enrollment
  • Known contraindications to IUD placement
  • Contraindication to lidocaine
  • IUD exchange
  • Previous unsuccessful attempt for IUD by the same practitioner

Key Trial Info

Start Date :

June 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 16 2024

Estimated Enrollment :

246 Patients enrolled

Trial Details

Trial ID

NCT06532162

Start Date

June 30 2022

End Date

August 16 2024

Last Update

January 27 2025

Active Locations (1)

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1

Mount Sinai Hospital

Toronto, Ontario, Canada, M5G1Z5