Status:

ACTIVE_NOT_RECRUITING

An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer

Lead Sponsor:

Ono Pharmaceutical Co. Ltd

Conditions:

Metastatic Pancreatic Cancer

Eligibility:

All Genders

20+ years

Phase:

PHASE1

Brief Summary

To investigate the tolerability and safety of ONO-7913 and ONO-4538 used in combination with modified FOLFIRINOX (mFFX therapy), the standard of care, as first-line treatment in patients with metastat...

Eligibility Criteria

Inclusion

  • 1\. Untreated metastatic pancreatic cancer
  • 2\. Life expectancy of at least 3 months
  • 3\. Patients with ECOG performance status 0 or 1

Exclusion

  • 1\. Patients with severe complication
  • 2\. Patients with multiple primary cancers

Key Trial Info

Start Date :

July 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2026

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT06532344

Start Date

July 30 2021

End Date

December 31 2026

Last Update

November 14 2024

Active Locations (9)

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Page 1 of 3 (9 locations)

1

National Cancer Center Hospital East

Kashiwa-shi, Chiba, Japan

2

Kanagawa Cancer Center

Yokohama, Kanagawa, Japan

3

Seirei Hamamatsu General Hospital

Hamamatsu, Shizuoka, Japan

4

Juntendo University Hospital

Bunkyō-Ku, Tokyo, Japan