Status:
NOT_YET_RECRUITING
Comparison of Efficacy of Oral Amoxicillin Versus Intravenous Ceftriaxone
Lead Sponsor:
RESnTEC, Institute of Research
Conditions:
Community-acquired Pneumonia
Eligibility:
All Genders
2-5 years
Phase:
NA
Brief Summary
The efficacy of oral amoxicillin is considered equal to that of ceftriaxone in community-acquired pneumonia among children. Also, there are some factors that contradict the usage of ceftriaxone, like ...
Detailed Description
The efficacy of oral amoxicillin is considered equal to that of ceftriaxone in community-acquired pneumonia among children. Also, there are some factors that contradict the usage of ceftriaxone, like ...
Eligibility Criteria
Inclusion
- Children of both gender
- Aged from 2 to 5 years
- With fever \>37.5 C (99.5 F)
- Will be presented with symptoms and signs of uncomplicated community acquired pneumonia
Exclusion
- Children requiring ICU care (having cyanosis SpO2 \< 85% requiring intubation within first day of admission or in state of shock)
- Children with conditions like congenital heart disease, chronic lung disease, chronic kidney disease, severe malnutrition, asthma, foreign bodies, sickle cell disease, and immunodeficiency
- Children with underlying anatomical disorders of the lung like pulmonary sequestration, tracheoesophageal fistula or congenital cystic adenoid malformation
- Children already on antibiotics
- Presence of any complication of community acquired pneumonia
- Patients having symptoms of multi-organ involvement/sepsis
- Hypersensitivity to Amoxicillin or Ceftriaxone
- Other co-existing infections like dengue, malaria, or measles
Key Trial Info
Start Date :
October 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2025
Estimated Enrollment :
114 Patients enrolled
Trial Details
Trial ID
NCT06532409
Start Date
October 1 2024
End Date
September 30 2025
Last Update
August 1 2024
Active Locations (1)
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1
Children Hospital
Lahore, Punjab Province, Pakistan, 54000