Status:
RECRUITING
Antimicrobial Efficacy of Nano-Based ICM on E.F
Lead Sponsor:
Tanta University
Conditions:
Enterococcus Faecalis Infection
Endodontically Treated Teeth
Eligibility:
All Genders
19-60 years
Phase:
NA
Brief Summary
This in-vivo study aims to evaluate the antimicrobial effect of nano based intracanal medications (Triple antibiotic-loaded chitosan nanoparticles and chlorohexidine loaded by silver nanoparticles) on...
Detailed Description
Success of root canal treatment is largely dependent on the elimination of harmful microorganisms and primarily bacteria from the root canal system through chemomechanical preparation and using intrac...
Eligibility Criteria
Inclusion
- Single rooted, single canal premolar teeth.
- Teeth indicated for non-surgical root canal retreatment.
- Teeth have signs and/or symptoms of post-treatment disease manifested by recurrent acute and/or chronic periapical abscess.
- Teeth have clinical signs and symptoms of endodontic failure as sensitivity to percussion, pain, swelling or fistula.
- Teeth with radiographic features of endodontic failure as persistent periapical lesion or widening of periodontal ligament.
- Symptomatic or asymptomatic teeth with short root canal filling indicated for prosthetic restoration
Exclusion
- Patients with any systemic diseases.
- Pregnant or lactating patients.
- Immunocompromised patients.
- Non-restorable tooth.
- Calcified root canal.
- Teeth with root fracture.
- Teeth with periodontal pocket deeper than 4mm.
- Teeth have procedural error like ledge, broken instrument, or perforation
Key Trial Info
Start Date :
January 2 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 2 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06533215
Start Date
January 2 2024
End Date
March 2 2025
Last Update
August 1 2024
Active Locations (1)
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1
Faculty of Dentistry
Tanta, Egypt