Status:
COMPLETED
Evaluation of the Relationship Between Optic Nerve Diameter and Optic Nerve Sheath Diameter Measured by Transorbital Sonography With Clinical, Radiological, and Electrophysiological Parameters in Multiple Sclerosis Patients
Lead Sponsor:
Kutahya Health Sciences University
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-50 years
Brief Summary
The primary aim of this study is to evaluate the reliability of optic nerve diameter (OND) and optic nerve sheath diameter (ONSD) measurements made with transorbital sonography (TOS) and magnetic reso...
Detailed Description
The study included 102 patients with MS-81 with relapsing-remitting MS (RRMS), 19 with secondary progressive MS (SPMS), and 2 with primary progressive MS (PPMS)-as well as 34 healthy controls, all sel...
Eligibility Criteria
Inclusion
- Being between the ages of 18-65
- Having been diagnosed with Multiple Sclerosis
- Undergoing disease-modifying therapy (DMT) for more than 6 months
- EDSS score ≤ 7
Exclusion
- Patients whose Multiple Sclerosis diagnosis is uncertain
- Having ocular pathology that may affect optic nerve measurements (e.g., glaucoma, high myopia, history of ocular surgery)
- Having major systemic diseases that may affect optic nerve measurements (e.g., diabetes mellitus, hypertension)
- EDSS score \> 7
- Having experienced a clinical relapse or optic neuritis within the last 6 months.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2024
Estimated Enrollment :
136 Patients enrolled
Trial Details
Trial ID
NCT06533930
Start Date
October 1 2023
End Date
April 1 2024
Last Update
August 29 2025
Active Locations (1)
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1
Kutahya Health Sciences University, Faculty of Medicine
Kütahya, Kütahya, Turkey (Türkiye), 43100