Status:
ACTIVE_NOT_RECRUITING
The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics
Lead Sponsor:
Dobri Kiprov
Collaborating Sponsors:
CIRCULATE, Inc.
Conditions:
Aging
Eligibility:
All Genders
50-95 years
Phase:
PHASE3
Brief Summary
The goal of this clinical trial is to assure the safety of long term therapeutic plasma exchange (TPE) with and without Intravenous Immunoglobulin (IVIG) and its effects on biomarkers and epigenetic b...
Eligibility Criteria
Inclusion
- Subjects over 50 years of age with or without chronic inflammatory condition
Exclusion
- Poor peripheral vascular access
- Diagnosis of active malignancy
- Late-stage Alzheimer's disease Any medical condition which may deteriorate because of plasma exchange procedures. These include, but are not limited to, symptomatic coronary artery disease, congestive heart failure and restrictive pulmonary disease (COPD). The investigators reserve the right to exclude anyone they feel may be harmed in any way by participating in the trial.
- Presence of active infection
- Alcohol or drug dependency
- Psychiatric disorder that will interfere with participation in the study (e.g., schizophrenia, bipolar disorder)
Key Trial Info
Start Date :
September 12 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06534450
Start Date
September 12 2022
End Date
August 1 2025
Last Update
August 2 2024
Active Locations (1)
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1
Global Apheresis
Mill Valley, California, United States, 94941