Status:
NOT_YET_RECRUITING
Trial Comparing Avg. Global Qual of Lifescore in Hypo Frac. RT vs Conv. Frac. in H&N Cancers
Lead Sponsor:
Tata Medical Center
Conditions:
Radiation Treatment
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Radiotherapy forms an integral part of Head and Neck cancer treatment in both definitive as well as adjuvant setting. This study explores the use of hypofractionated radiotherapy, delivering 55Gy in 2...
Detailed Description
Head and neck cancers comprise of cancers of arising from the epithelial lining of the lip, oral cavity, pharynx and larynx. The overall incidence of Head and Neck cancers continues to increase, despi...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- ECOG performance status 0 - 2.
- Patients diagnosed with invasive squamous cell cancer of the head and neck region which includes lip, oral cavity, nasopharynx, oropharynx, hypopharynx, supraglottis, glottis and subglottis.
- Patients who are being treated with curative intent treatment either with surgery followed by adjuvant radiotherapy with or without chemotherapy or definitive chemoradiation.
- Patients must have a histopathological proof of malignancy, such as biopsy or post operative histopathology report. Biopsies or surgeries done outside must have been reviewed for pathological confirmation and specimen adequacy at the treating institute.
- Patients with non metastatic cancer, optimally staged with the following:
- Contrast enhanced CT scan of the neck and thorax for cancer lip, oral cavity, oropharynx, hypopharynx, supraglottis, glottis and subglottis
- Magnetic Resonance Imaging of the neck and CT thorax for cancer of nasopharynx
Exclusion
- Concurrent illness like severe cardiac, renal or hepatic dysfunction and, including severe infection that may jeopardise the ability of the patient to undergo the procedures outlined in this protocol with reasonable safety
- Serious medical or psychiatric conditions that might limit the ability of the patient to comply with the protocol.
Key Trial Info
Start Date :
August 7 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2031
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT06536699
Start Date
August 7 2024
End Date
July 1 2031
Last Update
August 5 2024
Active Locations (1)
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1
Tata Medical Center
Kolkata, West Bengal, India, 700160