Status:
RECRUITING
Abbreviated MRI Using Gadoxetic Acid Versus CT for Surveillance of Recurrent HCC After Curative Treatment
Lead Sponsor:
Asan Medical Center
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Hepatocellular carcinoma (HCC) often has a poor prognosis after curative treatment due to frequent recurrence. Post-surgery, 60-70% of HCC patients experience recurrence, rising to 80% after ablation ...
Detailed Description
A total of 455 subjects will be evaluated by two rounds of tests with both abbreviated MRI (AMRI) and dynamic CT to detect the occurrence of secondary HCC. These two imaging tests are planned to be pe...
Eligibility Criteria
Inclusion
- Patients with more than two years without recurrence after curative treatment (surgery or local ablation) for HCC
- Patients with no history of systemic treatment, radiation therapy, or trans-arterial chemoembolization for HCC
- Older than 20 years of age
- Eastern Cooperative Oncology Group performance status of 0-2
- Patient is able to comply with scheduled visits, evaluation plans, and other study procedures
- Patient is willing to provide written informed consent
Exclusion
- Active or suspected cancer, or a history of malignancy where the risk of recurrence is equal or higher than 20% within 2 years.
- Significant medical comorbidities in which survival is predicted to be less than 3 years
- Estimated glomerular filtration rate \< 30 mL/min/1.73m²
- Patient not eligible for applying LI-RADS criteria, such as Budd-Chiari Syndrome
- Precautions for MRI (cardiac pacemaker, severe claustrophobia that may interfere with protocol compliance).
- Any other condition which, in the opinion of the Investigator, would make the patient unsuitable for enrollment or could interfere with completing the study
Key Trial Info
Start Date :
December 12 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
455 Patients enrolled
Trial Details
Trial ID
NCT06537193
Start Date
December 12 2024
End Date
December 31 2028
Last Update
May 31 2025
Active Locations (1)
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1
Asan Medical Center
Seoul, Songpa-gu , 88, Olympic-ro 43-gil, South Korea, 05505