Status:
RECRUITING
Hypofractionated External Beam Radiotherapy With Adaptive Planning for Endometrial and Cervical Cancers
Lead Sponsor:
Jonsson Comprehensive Cancer Center
Conditions:
Endometrial Cancer
Cervical Cancer
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
After surgery to remove the main endometrial and/or cervical tumor, most women receive radiation therapy. This study uses hypo-fractionated radiation therapy, which is a type of radiation therapy in w...
Detailed Description
The investigators hypothesize that adaptive planning with either computed tomography (CT) or magnetic resonance imaging (MRI) guidance may offer improved SBRT plans for postoperative gynecological can...
Eligibility Criteria
Inclusion
- Histologically confirmed endometrial or cervical cancer
- Surgical resection of the primary tumor
- International Federation of Gynecology and Obstetrics (FIGO) Stage IA-IVB endometrial cancer OR FIGO Stage IA-IIA cervical cancer that meets indications for receiving adjuvant pelvic radiotherapy alone as standard of care
- Age ≥ 18 years old
- Karnofsky performance status (KPS) ≥ 60 or Eastern Cooperative Oncology Group (ECOG) 0-2
Exclusion
- Must not meet indications for receiving concurrent chemotherapy as standard of care
- Active treatment of a separate malignancy
- History of prior irradiation to the area to be treated
Key Trial Info
Start Date :
July 24 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 26 2032
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06538337
Start Date
July 24 2024
End Date
July 26 2032
Last Update
August 15 2025
Active Locations (1)
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1
University of California at Los Angeles
Los Angeles, California, United States, 90095