Status:
COMPLETED
Impact of High Versus Lower Oxygen Fraction Prior to Extubation on Postoperative Pulmonary Atelectasis Measured With EIT
Lead Sponsor:
Beth Israel Deaconess Medical Center
Conditions:
Atelectasis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patients undergoing general anesthesia require mechanical ventilation (artificial delivery of air and oxygen to their lungs). It is well known that during mechanical ventilation, so-called atelectasis...
Detailed Description
This study is a single blinded randomized controlled trial with and aims to assess whether the use of 100% oxygen before extubation favors postoperative atelectasis formation compared to the use of lo...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Elective surgery with general anesthesia and endotracheal intubation
- Expected duration of surgery 1-5 hours
- Consent obtained from patient
Exclusion
- Patients with inability to give written informed consent
- American Society of Anesthesiologists (ASA) physical status\> IV
- Morbid obesity BMI \> 40
- Suspected pregnancy and lactation
- Cardiac or thoracic surgery
- Patients with thoracic epidural catheters
- Patients with active implantable devices, such as pacemakers, cardioverter defibrillators, or neurostimulators
- Compromised airways
- Impaired oxygenation at baseline or during surgery
Key Trial Info
Start Date :
September 27 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 22 2025
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06538740
Start Date
September 27 2024
End Date
May 22 2025
Last Update
September 25 2025
Active Locations (1)
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1
Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School
Boston, Massachusetts, United States, 02215