Status:
RECRUITING
Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
Florida State University
University College Dublin
Conditions:
Obesity
Eligibility:
All Genders
18+ years
Brief Summary
Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity. Yet, the exact mechanisms governing its eff...
Detailed Description
HYPOTHESIS AND PRIMARY OBJECTIVE So far, studies of ingestive behaviour in humans have produced ambiguous results. Moreover, direct measurements of ingestive behaviour in humans after BS are still ra...
Eligibility Criteria
Inclusion
- Age ≥ 18 year
- BMI ≥ 35 kg/m2 for patients with planned RYGB or SG operation
- BMI ≥ 30 kg/m2 for external controls affected by obesity but no planned RYGB or SG within the next 12 months, and
- BMI ≥ 18.5 kg/m2 and ≤ 24.9 kg/m2 for controls without obesity.
Exclusion
- history of previous bariatric operations and/ or revisional surgery (e.g., alteration of limb lengths after primary RYGB),
- smoking,
- established diagnosis of type 1 or 2 diabetes mellitus, and
- polycystic ovary syndrome (PCOS).
Key Trial Info
Start Date :
February 13 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2027
Estimated Enrollment :
420 Patients enrolled
Trial Details
Trial ID
NCT06538948
Start Date
February 13 2024
End Date
August 31 2027
Last Update
August 6 2024
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Männedorf
Männedorf, Canton of Zurich, Switzerland, 8708
2
University Hospital Zurich, Department of Surgery and Transplantation
Zurich, Switzerland, 8091