Status:
COMPLETED
Periodontal Therapy Effect on the Ratio of TNF-α to IL-10 in Periodontis With/Out DM
Lead Sponsor:
Ain Shams University
Conditions:
Periodontitis Generalized
Eligibility:
All Genders
20-50 years
Phase:
NA
Brief Summary
Periodontitis is a chronic inflammatory disease affecting the periodontium, characterized by irreversible damage to the gingiva, periodontal ligament, and alveolar bone. It is prevalent among adults, ...
Detailed Description
A single-blinded, randomized clinical trial was conducted on 36 patients with generalized periodontitis, recruited from Ain-Shams University's outpatient clinic. Patients were divided into three group...
Eligibility Criteria
Inclusion
- Both genders. Age (20-50 ) years old. Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study.
- Generalized Periodontitis patients . Having at least 20 tooth excluding wisdoms. Systemically free according to the modified Burkett's health history questionnaire except for diabetes mellitus (Burket, Greenberg and Glick 2003).
Exclusion
- Smokers.
- Intake of immunosuppressive drugs, antibiotics or anti-inflammatory drugs throughout the last three months prior to the study .
- status of pregnancy or lactation.
- allergy to local anesthetic.
- Prisoners .
- The vulnerable group ; mentally and physically disabled patients .
Key Trial Info
Start Date :
March 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2024
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT06539039
Start Date
March 1 2024
End Date
May 1 2024
Last Update
August 6 2024
Active Locations (1)
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1
Dentistry
Cairo, Organization of African Unity St, El-Qobba Bridge, Egypt, 11566