Status:

ENROLLING_BY_INVITATION

An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis

Lead Sponsor:

UCB Biopharma SRL

Conditions:

Generalized Myasthenia Gravis

Eligibility:

All Genders

2+ years

Phase:

PHASE3

Brief Summary

The purpose of the study is to assess the long term safety and tolerability of additional 6-week treatment cycles with rozanolixizumab in pediatric participants with generalized Myasthenia Gravis (gMG...

Eligibility Criteria

Inclusion

  • Study participant must meet one of the following:
  • Study participant completed MG0006 according to the protocol
  • Study participant completed the MG0006 Treatment Period and has a worsening of generalized myasthenia gravis (gMG) symptoms in the Observation Period of MG0006

Exclusion

  • Study participant met any mandatory withdrawal or mandatory permanent investigational medicinal product (IMP) discontinuation criteria in MG0006 or permanently discontinued IMP
  • Study participant has a known hypersensitivity to any components of the IMP or other neonatal Fc receptor (FcRn) drugs
  • Study participant has any laboratory abnormality that, in the opinion of the Investigator, is clinically significant, has not resolved at Baseline, and could jeopardize or compromise the study participant's ability to participate in this study

Key Trial Info

Start Date :

October 8 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 17 2027

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT06540144

Start Date

October 8 2024

End Date

August 17 2027

Last Update

December 15 2025

Active Locations (10)

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Page 1 of 3 (10 locations)

1

Mg0008 40290

Bologna, Italy

2

Mg0008 40144

Milan, Italy

3

Mg0008 40733

Napoli, Italy

4

Mg0008 20340

Fuchu-shi, Japan