Status:

RECRUITING

Efficacy of Light Therapy in Treatment of Chronic Cluster Headache

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Cluster Headache

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Cluster headache is a primary headache. The chronic form of the disease is often difficult to treat. It is now considered a chronobiological disease. This chronobiological character is based on clinic...

Eligibility Criteria

Inclusion

  • Male or female, of 18 years years old or more;
  • Diagnosis of chronic cluster headache according to ICHD-3 criteria;
  • Number of seizures during baseline equal to at least 24;
  • Stability of prophylactic treatment for at least 1 month and commitment not to change it for the duration of the study;
  • Patient affiliated to the French social security system.
  • Patient who understands and speaks French correctly;
  • Patient who has given free and informed written consent.

Exclusion

  • Contraindication to the use of light therapy: use of a photosensitizing treatment;
  • Ophthalmological history: cataract, macular degeneration, glaucoma, retinitis pigmentosa;
  • Patients who work at night;
  • Other neurological, psychiatric or developmental pathologies considered incompatible with the study;
  • Background treatment of cluster headache with melatonin;
  • Persons protected by articles L1121-5, L1121-6 and L1121-8 of the French Public Health Code (pregnant or breast-feeding women, persons deprived of their liberty by judicial decision, socially vulnerable persons, adults incapable or unable to express their consent).

Key Trial Info

Start Date :

February 6 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 5 2027

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06540651

Start Date

February 6 2025

End Date

May 5 2027

Last Update

March 17 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Hopital La Timone

Marseille, France, 13005

2

Hôpital de Cimiez

Nice, France, 06000