Status:
RECRUITING
A New Strategy for Preoperative Drainage of Resectable Pancreatic Head Cancer Combined Severe Obstructive Jaundice
Lead Sponsor:
Ruijin Hospital
Conditions:
Pancreatic Cancer
Obstructive Jaundice
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Severe obstructive jaundice caused by pancreatic head cancer usually requires preoperative biliary drainage, but its necessity and effectiveness are controversial, and specific strategies lack clear s...
Eligibility Criteria
Inclusion
- Pathological diagnosis of pancreatic head cancer, or clinical diagnosis of pancreatic head cancer after multidisciplinary discussion, clear presence of obstructive jaundice caused by pancreatic head tumor, and planned to undergo radical pancreaticoduodenectomy
- Preoperative imaging stage is resectable
- Baseline serum total bilirubin ≥ 250μmol/L, and no history of preoperative biliary drainage
- Age \>18 and ≤75 years old
- ECOG(Eastern Cooperative Oncology Group) physical score ≤ 2
- Signed informed consent, received preoperative endoscopic biliary drainage (ERCP) and radical surgery timing evaluation
Exclusion
- Combined with other malignant tumors
- Combined with uncontrolled medical diseases or organ dysfunction and other absolute counterindications for surgery
- Pregnant and lactating women
- Patients who cannot tolerate preoperative biliary drainage or radical surgery
- Other situations that are not suitable for inclusion in clinical trials
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
360 Patients enrolled
Trial Details
Trial ID
NCT06541340
Start Date
August 1 2024
End Date
December 31 2026
Last Update
August 7 2024
Active Locations (1)
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1
Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China, 200025