Status:

RECRUITING

Prognostic Model for Long-Term Cardiac Function After Pulmonary Embolism Based on Dynamic Electrocardial Signal and Circulating Biomarkers

Lead Sponsor:

China-Japan Friendship Hospital

Conditions:

Pulmonary Embolism

Eligibility:

All Genders

18+ years

Brief Summary

Pulmonary embolism (PE) is a highly morbid and fatal cardiovascular disease. Right ventricular dysfunction (RVD) secondary to PE indicates a poor prognosis and serves as a critical basis for risk stra...

Detailed Description

Long-term functional impairment after acute PE has been increasingly concerned in recent years. Our previous meta-analysis indicated that 34% PE patients had RVD at 1 year after an acute episode. Howe...

Eligibility Criteria

Inclusion

  • Age ≥18 years;
  • Patients with confirmed diagnosis of PE (refer to the 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism);
  • Onset ≤14 days from diagnosis; (4) Risk stratification of intermediate-low risk, intermediate-high risk, and high-risk according to the 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism;
  • 5\) Patients agree to sign informed consent.

Exclusion

  • A previous diagnosis of VTE with no evidence of recurrence, re-hospitalisation or treatment.
  • Unable to attach the cardiac acquisition system due to chest surgery, localised damage, allergy, etc.
  • Unable to complete the 1-year follow-up.
  • Unable to operate portable mapping due to cognitive impairment, lack of a smartphone, etc.

Key Trial Info

Start Date :

July 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT06541353

Start Date

July 1 2024

End Date

June 30 2026

Last Update

August 7 2024

Active Locations (1)

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China, 100029

Prognostic Model for Long-Term Cardiac Function After Pulmonary Embolism Based on Dynamic Electrocardial Signal and Circulating Biomarkers | DecenTrialz