Status:

COMPLETED

Image-Guided Pleural Needle Biopsy in Pleural Diseases

Lead Sponsor:

Eskisehir Osmangazi University

Conditions:

Biopsy

Diagnosis

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

In recent observational studies show that ultrasound guidance generally increases the success of pleural needle biopsies, it has been shown that the diagnostic success of needle biopsies is compromise...

Detailed Description

AIM A significant proportion of the most common exudative pleural effusions, approximately 40-50%, remain undiagnosed despite repeated thoracentesis and associated diagnostic procedures, including cyt...

Eligibility Criteria

Inclusion

  • Evidence of exudative pleural effusion for which a specific diagnosis could not be established by clinical, radiological, laboratory, and cytological examination
  • Patients who do not have a high risk of side effects or contraindications for the procedures in question (without bleeding diathesis, who can be positioned appropriately for the biopsy procedure)
  • Willingness to participate in the study
  • Willingness to undergo an invasive procedure
  • Willingness to undergo written consent for randomization and participation in the study.

Exclusion

  • Presence of parapneumonic effusion
  • Patients with consciousness problems
  • Any contraindication to pleural biopsy (patients with pathology in the chest wall biopsy site (infection) that would preclude biopsy, patients who are taking blood thinners (anticoagulants/antiaggregants) and cannot be interrupted for the procedure to be performed or can be interrupted by bridging with another blood thinner.)
  • Any other systemic disease that could interfere with thoracic computed tomography or ultrasonography assessment.

Key Trial Info

Start Date :

February 11 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 2 2024

Estimated Enrollment :

148 Patients enrolled

Trial Details

Trial ID

NCT06541470

Start Date

February 11 2021

End Date

June 2 2024

Last Update

August 7 2024

Active Locations (5)

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Page 1 of 2 (5 locations)

1

ESOGU Medical Faculty Department of Chest Diseases

Eskişehir, Meselik - Eskisehir, Turkey (Türkiye), 26040

2

Muzaffer Metintas

Eskişehir, Meselik, Turkey (Türkiye), 26040

3

Selma Metintas

Eskişehir, Meselik, Turkey (Türkiye), 26040

4

ESOGU Lung and Pleural Cancers Clinical and Research Center

Eskişehir, Meselik, Turkey (Türkiye), 26220