Status:
COMPLETED
Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal Cancer
Lead Sponsor:
Fudan University
Conditions:
Rectal Cancer
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is determine whether a trimodel prehabilitation program (combined with physical exercise, nutrition supplement and mental support) during neoadjuvant chemoradiotherapy can he...
Detailed Description
This study is a prospective, single-center, randomized control trial. Including criteria were (1) Age between 18 and 80 years; (2) Histologically confirmed rectal adenocarcinoma；(3) Performance status...
Eligibility Criteria
Inclusion
- Patients with rectal cancer undergoing/scheduled for neoadjuvant chemoradiotherapy
- Fried Frailty score≥2 (intermediately frail or frail)
- Written consent informed
Exclusion
- Co-morbiditie contraindicating physical exercise or causing disturbances of conciousness (dementia, Parkinson Disease, previous stroke with paresis, taking carbidopa/levodopa, donepezil or antidepressants)
- Emergent surgery
- ASA grade IV-V
- Pregnancy (absence confirmed by serum/urine β-HCG) or breast-feeding
- Known drug abuse/ alcohol abuse
Key Trial Info
Start Date :
December 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2024
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT06542354
Start Date
December 20 2021
End Date
March 20 2024
Last Update
August 7 2024
Active Locations (1)
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1
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China, 200032