Status:
RECRUITING
Studying Phenotypes of Gestational Diabetes Mellitus in an Asian Pregnant Cohort
Lead Sponsor:
National University Health System, Singapore
Conditions:
Gestational Diabetes
Pregnancy Related
Eligibility:
FEMALE
21-45 years
Brief Summary
Gestational diabetes mellitus (GDM) is a transient hyperglycemic condition identified during pregnancy in women without a history of chronic diabetes. Evidence indicates that GDM can lead to various a...
Detailed Description
The transient hyperglycemia first identified during pregnancy is known as gestational diabetes mellitus (GDM). GDM increases the risks of adverse pregnancy and neonatal outcomes, such as pre-eclampsia...
Eligibility Criteria
Inclusion
- Gestational age of ≤ 13 weeks 6 days
- Overweight and obese subjects with BMI of 23kg/m² - 24.9kg/m² and ≥ 25.0kg/m², respectively
- Aged 21-45 years with singleton pregnancy
- Plan to be followed up during the whole pregnancy and deliver at NUH
- Chinese, Malay or Indian ethnicity for pregnant subject
- Can complete questionnaires in English language
- Willing to wear continuous glucose monitoring device at least for 7 days at each required clinic visit
Exclusion
- Participants who are not Singapore citizens or Singapore Permanent Residents, not intending to eventually deliver in Singapore National University Hospital and to reside in Singapore for the next 2 years
- Have serious skin conditions (eg. eczema) that precludes wearing the sensor for 14 days
- With history of Type 1 diabetes or Type 2 diabetes
- With chronic preexisting life-threatening conditions including pancreatic cancer, end-stage kidney dysfunction, and psychosis
- Unable to read or speak English
Key Trial Info
Start Date :
October 3 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT06542718
Start Date
October 3 2022
End Date
July 1 2026
Last Update
May 28 2025
Active Locations (1)
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1
Department of Obstetrics & Gynaecology
Singapore, Singapore, 117549