Status:

COMPLETED

Low-Cost Platelet-Rich Plasma for Hemarthropathy

Lead Sponsor:

University of Utah

Conditions:

Hemarthrosis

Hemophilia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Orthopedic complications can be injuries or diseases that affect the bones, muscles, and joints. Hemarthropathy is due to bleeding disorders, most commonly hemophilia, and can result in severe issues ...

Detailed Description

This study will be performed as a prospective, single arm study. Consecutive patients eligible for a standard-of-care injection will be enrolled from the Utah Center for Bleeding and Clotting Disorder...

Eligibility Criteria

Inclusion

  • Patients of any adult age with symptomatic hemarthropathy of the ankle, knee, or elbow, based on radiographs within the last 24 months.
  • Patients must have failed at least six weeks of conventional conservative treatments (such as medication or physical therapy).

Exclusion

  • Exclusion criteria will include recent (last two years) surgery to the affected joint, prior joint replacement.
  • Prior orthobiologic injection into the affected joint.
  • Thrombocytopenia
  • Inability to receive factor prior to PRP injection.
  • Active systemic or local infection at the site of injection,
  • Non-ambulatory patients
  • Body mass index (BMI) over 50
  • Recent (six month) or current corticosteroid injection/intake.
  • Patients with hemarthropathy in multiple joints will be eligible for up to 2 joints if multiple fit the criteria.

Key Trial Info

Start Date :

July 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 5 2025

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT06543368

Start Date

July 23 2024

End Date

May 5 2025

Last Update

November 17 2025

Active Locations (1)

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1

University of Utah

Salt Lake City, Utah, United States, 84108