Status:

RECRUITING

Harm Reduction for Smokers With Mental Illness

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Collaborating Sponsors:

Dartmouth College

Fordham University

Conditions:

Tobacco Dependence

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are no...

Eligibility Criteria

Inclusion

  • Diagnostic Criteria (must have one to be eligible):
  • Schizophrenia
  • Bipolar disorder
  • Major Depressive Disorders
  • Posttraumatic disorder
  • Other anxiety disorders
  • Additional
  • 21 years or older;
  • English-speaking;
  • Daily smoker (at least 10 cigarettes/day);
  • At least one quit attempt in the past 5 years using evidence- based pharmacotherapy or behavioral cessation support;
  • Not currently interested in quitting.

Exclusion

  • Currently residing in a nursing home;
  • Current diagnosis of Asthma;
  • Cognitive impairment (score \<26 on the Telephone Interview for Cognitive Status (TICS);
  • Current use of e-cigarettes (\>once a week);
  • Psychiatric instability (hospitalized in the past month);
  • Current AND moderate to severe substance use disorder;
  • Pregnant or planning to become pregnant;
  • Use of any smoked products other than cigarettes;
  • Current unstable medical illness making e-cigarette unsafe (e.g., recent heart attack, cancer);
  • Participation in SWITCH IT pilot study.

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2028

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT06543407

Start Date

October 1 2024

End Date

March 31 2028

Last Update

October 17 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Seven Counties Services

Louisville, Kentucky, United States, 40203

2

Homer Stryker MD School of Medicine (WMed)

Kalamazoo, Michigan, United States, 49008