Status:

RECRUITING

Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?

Lead Sponsor:

Brooke Army Medical Center

Conditions:

Low Back Pain

Eligibility:

All Genders

18-64 years

Phase:

NA

Brief Summary

Conditioned pain modulation (CPM) a measure of the effectiveness of the descending pain pathway and therefore a measure of the body's ability to perform endogenous analgesia. In subjects with normal f...

Eligibility Criteria

Inclusion

  • DEERS eligible
  • English speaking
  • Age 18-64 years
  • ODI baseline ≥25%
  • NPRS baseline ≥3/10
  • Low back pain symptoms greater than 3 months
  • Must be able to commit to at least six weeks of physical therapy interventions

Exclusion

  • Serious spinal pathology (acute fracture, active cancer, inflammation, inflammatory arthropathy)
  • Low back pain symptoms radiating below the knee
  • Pregnancy
  • Diagnosed neurological disease including traumatic brain injury, multiple sclerosis, chronic regional pain syndrome, and fibromyalgia.
  • History spinal surgery
  • Currently under litigation related to low back pain
  • Currently going through Medical Evaluation Board (MEB)
  • Retiring or separating from the military within a year

Key Trial Info

Start Date :

September 19 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT06544525

Start Date

September 19 2024

End Date

July 1 2025

Last Update

April 23 2025

Active Locations (1)

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Brooke Army Medical Center

Fort Sam Houston, Texas, United States, 78234