Status:
COMPLETED
Arthroscopic Debridement Followed by Intra-articular Injection of Micro-fragmented Adipose Tissue in Patients Affected by Knee Osteoarthritis
Lead Sponsor:
Istituto Clinico Humanitas
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
18+ years
Brief Summary
Background/Objectives: Micro-fragmented adipose tissue is emerging as a promising option for the treatment of various diseases including knee osteoarthritis (OA), though clinical trials are often limi...
Detailed Description
Patients were placed in a supine position and Betadine was used to treat the abdomen. Anesthesia was performed using disposable blunted cannulas with a modified Klein solution (a mixture of 250 ml of...
Eligibility Criteria
Inclusion
- age \> 18 years, patients affected by radiologically confirmed knee OA according to Kellgren-Lawrence classification, not responsive to at least 3 months of conservative treatment (e.g. physical therapy, exercise).
Exclusion
- recent traumatic events involving the index joint, chondromatosis, intra-articular injections of any type in the previous 6 months, malignancy, pregnancy, patients on anticoagulant therapy or suffering from coagulopathies and related disorders, systematic disorders affecting the joints (i.e rheumatoid arthritis). Enrolled patients underwent a knee radiograph (antero-posterior, Rosenberg and lateral projections) as well as MRI before the procedure to stage knee OA and evaluate potential intra-articular loose bodies or diseases different from knee OA (e.g tumors or focal cartilage lesions).
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2024
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT06545266
Start Date
January 1 2016
End Date
January 1 2024
Last Update
August 9 2024
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