Status:

COMPLETED

Effects of Human Milk Oligosaccharide Ingestion on Weight Loss and Markers of Health

Lead Sponsor:

Advanced Protein Technologies Corporation

Conditions:

Weight Loss

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

A randomized, double-blind, placebo-controlled, parallel arm study of 2'-fucosyllactose (2'-FL) was conducted in healthy males and females between the ages of 18 and 65 at the time of consent. 2'-FL i...

Detailed Description

Objective: To investigate the effects of daily supplementation with 3 g/day of 2'-fucosyllactose (2'-FL) compared to 3 g/day of maltodextrin placebo on muscle mass preservation, strength, and health m...

Eligibility Criteria

Inclusion

  • Men and women the ages of 18 to 65 at the time of consent
  • Ability to comply with study procedures
  • Availability to complete the study based on duration of individual visits and scheduling requirements
  • Body mass index (BMI) between 25 and 40 kg/m2 and/or body fat less than 30%, with a preference between a BMI of 25 - 32 kg/m2, and a desire to lose weight and participate in a fitness exercise program

Exclusion

  • Pregnant, breastfeeding, or wish to become pregnant during the study
  • Planning major changes in lifestyle (i.e., diet, dieting, exercise level, travel) during the study
  • Recent history (\< 3 months) of exercise training or weight loss (\> 5%)
  • Orthopedic limitation preventing participation in a general fitness program
  • Uncontrolled heart disease, hypertension, diabetes, thyroid disease, cancer, neurological disease, or untreated psychotic or major depressive disorder in which participation in a general fitness program is contraindicated
  • Taking weight loss dietary supplements or medications during the last 4 weeks
  • History within the previous 12 months of alcohol or substance abuse
  • Heavy smoking (\> 1 pack/day within the past 3 months)
  • Known allergy to milk, lactose, or any other milk product

Key Trial Info

Start Date :

May 4 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 22 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06547801

Start Date

May 4 2023

End Date

February 22 2024

Last Update

August 14 2024

Active Locations (1)

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1

Exercise & Sport Nutrition Lab, Department of Kinesiology and Sport Management, Texas A&M University, College Station

College Station, Texas, United States, 77843