Status:

COMPLETED

Effects of tES Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia

Lead Sponsor:

Northeast Normal University

Conditions:

Schizophrenic Patients

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial electrical stimulation (tES) and retrieval practice have been demonstrated as...

Detailed Description

1. Stimulation phase: In the tDCS group, the anode was placed over the left DLPFC (F3), and the cathode was placed over the contralateral supraorbital area (FP2). A direct current of 2mA was appli...

Eligibility Criteria

Inclusion

  • Meeting the diagnostic criteria for schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5);
  • Aged 18 years or older, regardless of gender, with an educational level of elementary school or above;
  • All patients received stable-level antipsychotic medication treatment, were in a stable phase of disease treatment, able to understand the testing requirements, and cooperated to complete all research tasks;
  • No history of neurological disorders or other serious physical illnesses, and no history of intellectual disability;
  • No color blindness, color weakness, or other color vision impairments, with normal vision or corrected vision.

Exclusion

  • Clear cognitive impairment caused by somatic or cerebral organic lesions, such as cerebrovascular diseases, traumatic brain injury, etc;
  • Individuals with mental disorders caused by substance dependence or abuse, or the use of psychoactive substances;
  • History of brain injury or other central nervous system-related organic diseases;
  • Individuals at significant risk of suicide or harming others;
  • Participation in similar experiments in the past 30 days prior to baseline.

Key Trial Info

Start Date :

August 30 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2024

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT06547996

Start Date

August 30 2024

End Date

October 30 2024

Last Update

November 15 2024

Active Locations (1)

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1

Northwest Normal University

Lanzhou, Gansu, China, 730070