Status:
RECRUITING
Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)
Lead Sponsor:
Jinan Central Hospital
Conditions:
Acute Ischemic Stroke
Atrial Fibrillation
Eligibility:
All Genders
18+ years
Brief Summary
The main purpose of this study is to investigate the safety and outcomes of different treatment strategies, including best medical therapy (OAC \[oral anticoagulation\], antiplatelet \[APT\]) and left...
Detailed Description
Ischemic stroke is the leading cause of disability and mortality globally. Atrial fibrillation（AF） is a well-established risk factor for ischemic stroke and responsible for up to one-third of all stro...
Eligibility Criteria
Inclusion
- Age \> 18 years old；
- Acute ischemic stroke with onset ≤ 14 days；
- Previously or during this hospitalization diagnosed with non-valvular atrial fibrillation;
- Informed consent obtained from the patient or his/her legal representative；
Exclusion
- Pacemaker, implantable cardioverter defibrillator or implantable cardiac monitor;
- Left atrial appendage has been removed or post occlusion device implantation;
- Transient AF secondary to other reversible disorders；
- Life expectancy less than 1 year;
- Patients that cannot complete subsequent follow-up (e.g. no fixed residence, overseas patients, etc.);
- Females who are pregnant or in lactation;
- Participating in other clinical trials that could confound the evaluation of the study;
- Other circumstances that the investigator considers inappropriate for participation or may pose a significant risk to patients.
Key Trial Info
Start Date :
November 15 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2029
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT06548269
Start Date
November 15 2024
End Date
May 31 2029
Last Update
May 22 2025
Active Locations (1)
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1
Jinan Central Hospital
Jinan, Shandong, China, 250013