Status:

ACTIVE_NOT_RECRUITING

A Real-world Study to Assess Safety of OZURDEX® (Dexamethasone Intravitreal Implant) in Adult Participants With Diabetic Macular Edema in China

Lead Sponsor:

AbbVie

Conditions:

Diabetic Macular Edema

Eligibility:

All Genders

18+ years

Brief Summary

The dexamethasone intravitreal implant (OZURDEX) delivers dexamethasone gradually to the retina over time. It is an approved drug for the treatment of diabetic macular edema (DME). This study will ass...

Eligibility Criteria

Inclusion

  • \- Participant scheduled to receive at least one intravitreal OZURDEX® injection for DME as per most current local approved label after its approval for DME in China.

Exclusion

  • Concurrent participation in interventional clinical research that required treatment or use of an investigational agent.
  • Participants for whom OZURDEX® is contraindicated:
  • Participants with known hypersensitivity to OZURDEX® or any components of this product.
  • Participants with active or suspected ocular or periocular infections including most viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, mycobacterial infections, and fungal diseases.
  • Participants with late stage glaucoma that cannot be controlled with medication alone.
  • Aphakia with ruptured posterior lens capsule.
  • Eyes with anterior chamber intraocular lenses (ACIOL), iris- or scleral-fixated intraocular lenses, and ruptured posterior lens capsule.

Key Trial Info

Start Date :

November 13 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT06548568

Start Date

November 13 2024

End Date

April 1 2027

Last Update

September 19 2025

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Peking University People'S Hospital /ID# 274505

Beijing, Beijing Municipality, China, 100034

2

Xiamen Eye Center of Xiamen University /ID# 268172

Xiamen, Fujian, China, 390000

3

Zhongshan Ophthalmic Center,SunYat-Sen University /ID# 274555

Guangzhou, Guangdong, China, 510623

4

Henan Provincial Eye Hosptial /ID# 272424

Zhengzhou, Henan, China, 450003