Status:

RECRUITING

Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound

Lead Sponsor:

Alexandria University

Conditions:

Preterm

Ventilator Lung; Newborn

Eligibility:

All Genders

1-24 years

Phase:

NA

Brief Summary

This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates \<37 gestational week wit...

Eligibility Criteria

Inclusion

  • Preterm \<37 wk. gestational age admitted to the NICU with spontaneous breathing and clinical manifestations of RD (tachypnea, nasal flaring, intercostal and subcostal retraction and or grunting).

Exclusion

  • Obvious major congenital abnormalities.
  • Any of the baby intubated for resuscitation or for other reasons.
  • Neonates need invasive mechanical ventilation.
  • Pulmonary hemorrhage.
  • Severe cardiovascular instability.
  • Cardiopulmonary arrest needing prolonged resuscitation.
  • Birth asphyxia (one-minute Apgar score ≤ 3).
  • Major cardiac diseases (not including patent ductus arteriosus).

Key Trial Info

Start Date :

November 20 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06550219

Start Date

November 20 2024

End Date

November 1 2025

Last Update

February 4 2025

Active Locations (1)

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Alexandria university, Elshattbi hospital

Alexandria, Egypt, 0354