Status:

NOT_YET_RECRUITING

Safety and Efficacy of Degradable Magnesium Metal Clips in Surgical Margins of Radical Surgery for Malignant Bone and Soft Tissue Tumors

Lead Sponsor:

Guangdong Provincial People's Hospital

Conditions:

Sarcoma, Soft Tissue

Sarcoma, Spindle Cell

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

To verify and evaluate the safety and efficacy of biodegradable magnesium metal clips in the surgical margins of radical surgery for bone and soft tissue malignant tumors.

Detailed Description

The purpose of this study is to verify and evaluate the safety and effectiveness of biodegradable magnesium metal clips in the surgical margins of radical surgery for bone and soft tissue malignant tu...

Eligibility Criteria

Inclusion

  • Participants must be of either gender, aged between 18 and 65 years;
  • Diagnosis must be confirmed pathologically as osteosarcoma, synovial sarcoma, liposarcoma, or other bone and soft tissue sarcomas;
  • Must have undergone standard chemotherapy and require en bloc resection;
  • Participants must voluntarily enroll and sign an informed consent form; willing to closely cooperate with the physician to comply with all study requirements, including participation in all follow-up and assessments.

Exclusion

  • Severe dysfunction of the heart, liver, kidney, lung, or brain.
  • Pregnant women or women who are breastfeeding.
  • History of autoimmune disease, HIV infection, history of immunosuppressive disorder, or currently taking immunosuppressive drugs.
  • History of syphilis (Treponema pallidum), active infection with hepatitis B or C, and positive for verified antigens.
  • Participation in any other clinical study currently or within 3 months prior to the screening visit.
  • Patients have any other conditions that the researcher deems unsuitable for the study. Age is between 18 to 75 years old.

Key Trial Info

Start Date :

August 25 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT06550765

Start Date

August 25 2024

End Date

December 31 2027

Last Update

August 13 2024

Active Locations (1)

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Guangdong provincial people's hospital

Guangzhou, Guangdong, China, 516008