Status:
RECRUITING
Prediction of Anxiety and Memory State
Lead Sponsor:
Columbia University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Rutgers University
Conditions:
Anxiety
Memory
Eligibility:
All Genders
18-55 years
Brief Summary
The purpose of this study is to look at how signals in the brain, body, and behavior relate to anxiety and memory function. This project seeks to develop the CAMERA (Context-Aware Multimodal Ecologica...
Detailed Description
CAMERA will record neural, physiological, behavioral, and environmental signals, as well as measurements from ecological momentary assessments (EMAs), to develop a continuous high-resolution predictio...
Eligibility Criteria
Inclusion
- Patients must have known or suspected Temporal Lobe Epilepsy.
- Native or proficient in speaking English or Spanish.
- Stereoelectroencephalography (sEEG) cases: The implant plan must include hippocampal head, body, and tail electrodes either unilaterally or bilaterally.
- 7th grade reading level (minimum level considered literate for adults)
Exclusion
- Hearing impaired (i.e., not corrected with a hearing aid)
- Unable to read the newspaper at arm's length with corrective lenses.
- Objective intellectual impairment (estimated IQ \< 70)
- Any history of Electroconvulsive Therapy or psychosis (except postictal psychosis for patients)
- Psychotic disorder (lifetime)
- Current Anxiety disorder, Major Depressive Disorder, or Bipolar Disorder
- Neurodegenerative diseases, presence of widespread brain lesions, language problems (other than naming difficulty)
- Medical conditions that could potentially affect cognitive performance (e.g., human immunodeficiency virus (HIV) infection, cancer with metastatic potential).
- Acute renal failure or end-stage renal disease
Key Trial Info
Start Date :
July 23 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06551090
Start Date
July 23 2024
End Date
December 1 2026
Last Update
January 17 2025
Active Locations (1)
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1
Columbia University
New York, New York, United States, 10032